Effect of Lifestyle Intervention on the Occurrence of Metabolic Syndrome and its Components in the Finnish Diabetes Prevention Study | Zendy

Pirjo IlanneParikka | Zendy; Johan G. Eriksson | Zendy; Jaana Lindström | Zendy; Markku Peltonen | Zendy; Sirkka Aunola | Zendy; Helena Hämäläinen | Zendy; Sirkka KeinänenKiukaanniemi | Zendy; Mauri Laakso | Zendy; Timo T. Valle | Zendy; Jorma Lahtela | Zendy; Matti Uusitupa | Zendy; Jaakko Tuomilehto | Zendy

Open Access

Effect of Lifestyle Intervention on the Occurrence of Metabolic Syndrome and its Components in the Finnish Diabetes Prevention Study

Author(s) -

Pirjo IlanneParikka,

Johan G. Eriksson,

Jaana Lindström,

Markku Peltonen,

Sirkka Aunola,

Helena Hämäläinen,

Sirkka KeinänenKiukaanniemi,

Mauri Laakso,

Timo T. Valle,

Jorma Lahtela,

Matti Uusitupa,

Jaakko Tuomilehto

Publication year - 2008

Publication title -

diabetes care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.636

H-Index - 363

eISSN - 1935-5548

pISSN - 0149-5992

DOI - 10.2337/dc07-1117

Subject(s) - medicine , diabetes mellitus , metabolic syndrome , intervention (counseling) , gerontology , endocrinology , psychiatry

OBJECTIVE—The aim of this secondary analysis of the Finnish Diabetes Prevention Study was to assess the effects of lifestyle intervention on metabolic syndrome and its components. RESEARCH DESIGN AND METHODS—A total of 522 middle-aged overweight men and women with impaired glucose tolerance were randomized into an individualized lifestyle intervention group or a standard care control group. National Cholesterol Education Program criteria were used for the definition of metabolic syndrome. RESULTS—At the end of the study, with a mean follow-up of 3.9 years, we found a significant reduction in the prevalence of metabolic syndrome in the intervention group compared with the control group (odds ratio [OR] 0.62 [95% CI 0.40–0.95]) and in the prevalence of abdominal obesity (0.48 [0.28–0.81]). CONCLUSIONS—The results suggest that lifestyle intervention may also reduce risk of cardiovascular disease in the long run.

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