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Amino-Terminal Brain Natriuretic Peptide is Related to the Presence of Diabetic Polyneuropathy Independently of Cardiovascular Disease
Author(s) -
Jeroni Jurado,
Juan Ybarra,
Marı́a Luisa Ferrándiz,
Lourdes Comerma,
José María Pou
Publication year - 2007
Publication title -
diabetes care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.636
H-Index - 363
eISSN - 1935-5548
pISSN - 0149-5992
DOI - 10.2337/dc07-0890
Subject(s) - medicine , diabetes mellitus , polyneuropathy , disease , brain natriuretic peptide , natriuretic peptide , endocrinology , cardiology , heart failure
Diabetic polineuropathy (DPN) is among the most common long-term complications of diabetes, affecting up to 50% of patients (1,2). Type 2 diabetes is considered by many to be a cardiovascular disease (CVD) (3).Plasma levels of the NH2-terminal fragment of the brain natriuretic peptide (NT-proBNP) have recently gained extreme importance as markers of myocardial dysfunction in type 2 diabetes. Excessive secretion of NT-proBNP is independently associated with coronary artery disease and overt nephropathy (4) in addition …

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