Circulating Vitamin D Concentrations in Two Neighboring Populations With Markedly Different Incidence of Type 1 Diabetes | Zendy

Hanna Viskari | Zendy; Anita Kondrashova | Zendy; Pentti Koskela | Zendy; Mikael Knip | Zendy; Heikki Hyöty | Zendy

Open Access

Circulating Vitamin D Concentrations in Two Neighboring Populations With Markedly Different Incidence of Type 1 Diabetes

Author(s) -

Hanna Viskari,

Anita Kondrashova,

Pentti Koskela,

Mikael Knip,

Heikki Hyöty

Publication year - 2006

Publication title -

diabetes care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.636

H-Index - 363

eISSN - 1935-5548

pISSN - 0149-5992

DOI - 10.2337/dc06-2559

Subject(s) - medicine , incidence (geometry) , diabetes mellitus , type 2 diabetes , endocrinology , type 1 diabetes , vitamin d and neurology , physiology , physics , optics

Recent studies have suggested that vitamin D deficiency may increase the risk of type 1 diabetes (1). In Finland, the incidence of type 1 diabetes is the highest in the world, while in the neighboring Karelian Republic of Russia, the incidence is approximately one-sixth that in Finland, despite no difference in HLA-conferred susceptibility (2). Thus, the reason(s) must be linked to environmental factors.We assessed vitamin D status in the Russian Karelian and Finnish populations to determine whether vitamin D could play a role in the huge difference observed in diabetes incidence. The geographical location in terms of daily sunlight exposure is …

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