Correspondence Between the International Diabetes Federation Criteria for Metabolic Syndrome and Insulin Resistance in a Cohort of Italian Nondiabetic Caucasians | Zendy

Giorgio Sesti | Zendy; Brunella Capaldo | Zendy; Paolo Cavallo Perin | Zendy; Stefano Del Prato | Zendy; Lucia Frittitta | Zendy; Simona Frontoni | Zendy; Marta Letizia Hribal | Zendy; Giulio Marchesini | Zendy; Giuseppe Paolisso | Zendy; Pier Marco Piatti | Zendy; Anna Solini | Zendy; Enzo Bonora | Zendy

Open Access

Correspondence Between the International Diabetes Federation Criteria for Metabolic Syndrome and Insulin Resistance in a Cohort of Italian Nondiabetic Caucasians

Author(s) -

Giorgio Sesti,

Brunella Capaldo,

Paolo Cavallo Perin,

Stefano Del Prato,

Lucia Frittitta,

Simona Frontoni,

Marta Letizia Hribal,

Giulio Marchesini,

Giuseppe Paolisso,

Pier Marco Piatti,

Anna Solini,

Enzo Bonora

Publication year - 2007

Publication title -

diabetes care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.636

H-Index - 363

eISSN - 1935-5548

pISSN - 0149-5992

DOI - 10.2337/dc06-2394

Subject(s) - medicine , insulin resistance , diabetes mellitus , cohort , metabolic syndrome , cohort study , endocrinology

In 2005, the International Diabetes Federation (IDF) released a consensus definition of the metabolic syndrome. The definition, intended to provide a feasible predictor of cardiovascular disease and type 2 diabetes, includes elevated waist circumference plus two of the following factors: reduced HDL cholesterol or raised blood pressure, triglycerides, or fasting glucose (1). Insulin resistance is a major pathogenic factor for the metabolic syndrome and may independently contribute to the risk of cardiovascular disease and type 2 diabetes (2). We assessed the diagnostic accuracy of the IDF definition of metabolic syndrome in identifying subjects with insulin resistance, defined as being in the lower quartile of insulin-stimulated glucose disposal ( M clamp) determined by a standardized hyperinsulinemic-euglycemic …

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