Progressive Loss of β-Cell Function Leads to Worsening Glucose Tolerance in First-Degree Relatives of Subjects With Type 2 Diabetes | Zendy

Miriam Cnop | Zendy; Josép Vidal | Zendy; Rebecca L. Hull | Zendy; Kristina M. Utzschneider | Zendy; Darcy B. Carr | Zendy; Todd Schraw | Zendy; Philipp E. Scherer | Zendy; Edward J. Boyko | Zendy; Wilfred Y. Fujimoto | Zendy; Steven E. Kahn | Zendy

Open Access

Progressive Loss of β-Cell Function Leads to Worsening Glucose Tolerance in First-Degree Relatives of Subjects With Type 2 Diabetes

Author(s) -

Miriam Cnop,

Josép Vidal,

Rebecca L. Hull,

Kristina M. Utzschneider,

Darcy B. Carr,

Todd Schraw,

Philipp E. Scherer,

Edward J. Boyko,

Wilfred Y. Fujimoto,

Steven E. Kahn

Publication year - 2007

Publication title -

diabetes care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.636

H-Index - 363

eISSN - 1935-5548

pISSN - 0149-5992

DOI - 10.2337/dc06-1834

Subject(s) - medicine , impaired glucose tolerance , endocrinology , type 2 diabetes , diabetes mellitus , first degree relatives , insulin , insulin resistance , tolbutamide , glucose tolerance test , family history

The relative roles of insulin resistance and beta-cell dysfunction in the pathogenesis of impaired glucose tolerance (IGT) and type 2 diabetes are debated. First-degree relatives of individuals with type 2 diabetes are at increased risk of developing hyperglycemia.

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