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Altered Kidney Graft High-Energy Phosphate Metabolism in Kidney-Transplanted End-Stage Renal Disease Type 1 Diabetic Patients
Author(s) -
Paolo Fiorina,
Gianluca Perseghin,
Francesco De Cobelli,
Chiara Gremizzi,
Alessandra Petrelli,
Lucilla D. Monti,
Paola Maffi,
Livio Luzi,
Antonio Secchi,
Alessandro Del Maschio
Publication year - 2007
Publication title -
diabetes care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.636
H-Index - 363
eISSN - 1935-5548
pISSN - 0149-5992
DOI - 10.2337/dc06-1324
Subject(s) - medicine , transplantation , kidney transplantation , kidney , diabetes mellitus , kidney disease , endocrinology , diabetic nephropathy , gastroenterology , renal function , urology , nephropathy
Diabetes, hypertension, dyslipidemia, obesity, nephrotoxicity of certain immunosuppressive drugs, and the persistence of a chronic alloimmune response may significantly affect graft survival in end-stage renal disease (ESRD) type 1 diabetic patients who have undergone kidney transplant. The aim of this study was to ascertain the impact of kidney alone (KD) or combined kidney-pancreas (KP) transplantation on renal energy metabolism.

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