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We thank Patil et al. (1) for their interest in our article (2) in which we established the gestational profile of placental exosomes in the plasma of women with gestational diabetes mellitus (GDM). A prospective cohort of patients was recruited at three time points during pregnancy for this study; therefore, we analyzed plasma at early gestation (i.e., 11–14 weeks) before GDM was diagnosed. Currently, there is no reliable early detection biomarker to identify women who are at risk for developing GDM (3). We established that the total number of …

diabetes

Response to Comment on Salomon et al. Gestational Diabetes Mellitus Is Associated With Changes in the Concentration and Bioactivity of Placenta-Derived Exosomes in Maternal Circulation Across Gestation. Diabetes 2016;65:598–609