Open AccessCathepsin D Drives the Formation of Hybrid Insulin Peptides Relevant to the Pathogenesis of Type 1 Diabetes
Author(s) -
Samantha A. Crawford,
Timothy A. Wiles,
Janet M. Wenzlau,
Roger Powell,
Gene Barbour,
Mylinh Dang,
Jason Groegler,
Jessie M. Barra,
KaLia S. Burnette,
Anita C. Hohenstein,
Rocky L. Baker,
Hubert M. Tse,
Kathryn Haskins,
Thomas Delong
Publication year - 2022
Publication title -
diabetes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.219
H-Index - 330
eISSN - 1939-327X
pISSN - 0012-1797
DOI - 10.2337/db22-0303
Subject(s) - proinsulin , cathepsin , pathogenesis , cathepsin d , proteases , nod mice , insulin , peptide , proteolysis , chemistry , nod , type 1 diabetes , diabetes mellitus , biology , islet , endocrinology , medicine , biochemistry , enzyme
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