Response to Comment on: Tessari et al. Roles of Insulin, Age, and Asymmetric Dimethylarginine on Nitric Oxide Synthesis In Vivo. Diabetes 2013;62:2699–2708 | Zendy

Paolo Tessari | Zendy

Open Access

Response to Comment on: Tessari et al. Roles of Insulin, Age, and Asymmetric Dimethylarginine on Nitric Oxide Synthesis In Vivo. Diabetes 2013;62:2699–2708

Author(s) -

Paolo Tessari

Publication year - 2013

Publication title -

diabetes

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.219

H-Index - 330

eISSN - 1939-327X

pISSN - 0012-1797

DOI - 10.2337/db13-1017

Subject(s) - nitric oxide , asymmetric dimethylarginine , diabetes mellitus , in vivo , insulin , dissociation (chemistry) , medicine , endocrinology , chemistry , pharmacology , biochemistry , biology , arginine , microbiology and biotechnology , amino acid

Ours as well as other recently published\udarticles challenge the somehow dogmatic concept\udabout the existence of a uniform and comprehensive\udstate of “insulin resistance,” a condition that should be\udconsidered multifaceted, and not defined just on the basis\udof the reduced insulin-mediated glucose disposal. This\udmore complex view may have relevant consequences\udnot only from a mechanistic but also from a therapeutic\udstandpoint

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