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Ours as well as other recently published\udarticles challenge the somehow dogmatic concept\udabout the existence of a uniform and comprehensive\udstate of “insulin resistance,” a condition that should be\udconsidered multifaceted, and not defined just on the basis\udof the reduced insulin-mediated glucose disposal. This\udmore complex view may have relevant consequences\udnot only from a mechanistic but also from a therapeutic\udstandpoint

diabetes

Response to Comment on: Tessari et al. Roles of Insulin, Age, and Asymmetric Dimethylarginine on Nitric Oxide Synthesis In Vivo. Diabetes 2013;62:2699–2708