Comment on: Maruthur et al. Does Genetic Ancestry Explain Higher Values of Glycated Hemoglobin in African Americans? Diabetes 2011;60:2434–2438 | Zendy

Samuel DagogoJack | Zendy

Open Access

Comment on: Maruthur et al. Does Genetic Ancestry Explain Higher Values of Glycated Hemoglobin in African Americans? Diabetes 2011;60:2434–2438

Author(s) -

Samuel DagogoJack

Publication year - 2011

Publication title -

diabetes

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.219

H-Index - 330

eISSN - 1939-327X

pISSN - 0012-1797

DOI - 10.2337/db11-1277

Subject(s) - glycated hemoglobin , genetic variants , diabetes mellitus , variance (accounting) , demography , hemoglobin , medicine , biology , genetics , endocrinology , type 2 diabetes , gene , genotype , sociology , accounting , business

Maruthur et al. (1) showed that European genetic admixture is inversely related to HbA1c levels among African Americans, although admixture explained less than 1% of the variance in HbA1c. Others have reported that genetic factors account for ∼60% of the variance in HbA1c (2). For unclear reasons, African Americans express higher HbA1c levels than Caucasians with similar blood glucose values (3 …

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