Comment on: Keenan et al. (2010) Residual Insulin Production and Pancreatic β-Cell Turnover After 50 Years of Diabetes: Joslin Medalist Study. Diabetes 2010;59:2846–2853 | Zendy

Kristina I. Rother | Zendy; David M. Harlan | Zendy

Open Access

Comment on: Keenan et al. (2010) Residual Insulin Production and Pancreatic β-Cell Turnover After 50 Years of Diabetes: Joslin Medalist Study. Diabetes 2010;59:2846–2853

Author(s) -

Kristina I. Rother,

David M. Harlan

Publication year - 2010

Publication title -

diabetes

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.219

H-Index - 330

eISSN - 1939-327X

pISSN - 0012-1797

DOI - 10.2337/db10-1207

Subject(s) - diabetes mellitus , insulin , medicine , endocrinology , endogeny , type 2 diabetes , cohort

We are pleased to find our previously published results (1,2) confirmed by the report of Keenan et al. (3). In their cohort of individuals with very long-standing type 1 diabetes, 67.4% of patients had residual endogenous insulin production, and in nine postmortem examinations of pancreatic tissue, insulin positive cells were found. However, we respectfully disagree that this …

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