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In the last 4 years, genome-wide association studies (GWASs) have revolutionized the complex disease genomics research worldwide. In the context of type 2 diabetes, GWASs have led to the discovery of several novel genetic markers that illuminated hitherto unknown biological pathways. Now, the validation of these type 2 diabetes–related priority single nucleotide polymorphisms (SNPs) (from GWASs) among different world populations is needed. Despite a very large burden of type 2 diabetes in India and the important question of possible genetic susceptibility among south Asians, the …

diabetes

Comment on: Chauhan et al. (2010) Impact of Common Variants of PPARG, KCNJ11, TCF7L2, SLC30A8, HHEX, CDKN2A, IGF2BP2, and CDKAL1 on the Risk of Type 2 Diabetes in 5,164 Indians. Diabetes;59:2068–2074