Association ofCDKAL1, IGF2BP2, CDKN2A/B, HHEX,SLC30A8,andKCNJ11With Susceptibility to Type 2 Diabetes in a Japanese Population
Author(s) -
Shintaro Omori,
Yasushi Tanaka,
Atsushi Takahashi,
Hiroshi Hirose,
Atsunori Kashiwagi,
Kohei Kaku,
Ryuzo Kawamori,
Yusuke Nakamura,
Shiro Maeda
Publication year - 2007
Publication title -
diabetes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.219
H-Index - 330
eISSN - 1939-327X
pISSN - 0012-1797
DOI - 10.2337/db07-0979
Subject(s) - single nucleotide polymorphism , type 2 diabetes , biology , genetics , population , linkage disequilibrium , peroxisome proliferator activated receptor gamma , genome wide association study , diabetes mellitus , genotype , endocrinology , gene , medicine , peroxisome , environmental health
Recently, several genes have been shown to be associated with an increased risk of type 2 diabetes by genome-wide association studies in white populations. To further investigate the involvement of these polymorphisms in conferring susceptibility to type 2 diabetes, we examined the association of 14 single nucleotide polymorphisms (SNPs) within 11 candidate loci with type 2 diabetes in a Japanese population.
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