Low Physical Activity Accentuates the Effect of the FTO rs9939609 Polymorphism on Body Fat Accumulation
Author(s) -
Camilla Andreasen,
Kirstine L. Stender-Petersen,
Mette Sloth Mogensen,
Signe S. Torekov,
Lise Wegner,
Gary L. Andersen,
Arne L. Nielsen,
Anders Albrechtsen,
Knut BorchJohnsen,
S. Rasmussen,
Jesper O. Clausen,
Annelli Sandbæk,
Torsten Lauritzen,
Lars Hansen,
Torben Jørgensen,
Oluf Pedersen,
Torben Hansen
Publication year - 2007
Publication title -
diabetes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.219
H-Index - 330
eISSN - 1939-327X
pISSN - 0012-1797
DOI - 10.2337/db07-0910
Subject(s) - fto gene , obesity , overweight , medicine , endocrinology , type 2 diabetes , allele , waist , genotype , minor allele frequency , body mass index , diabetes mellitus , odds ratio , polymorphism (computer science) , allele frequency , biology , genetics , gene
Three independent studies have shown that variation in the fat mass and obesity-associated (FTO) gene associates with BMI and obesity. In the present study, the effect of FTO variation on metabolic traits including obesity, type 2 diabetes, and related quantitative phenotypes was examined.
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