Splanchnic Spillover of Extracellular Lipase–Generated Fatty Acids in Overweight and Obese Humans | Zendy

Robert H. Nelson | Zendy; Rita Basu | Zendy; Christopher M. Johnson | Zendy; Robert A. Rizza | Zendy; John J. Miles | Zendy

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Splanchnic Spillover of Extracellular Lipase–Generated Fatty Acids in Overweight and Obese Humans

Author(s) -

Robert H. Nelson,

Rita Basu,

Christopher M. Johnson,

Robert A. Rizza,

John J. Miles

Publication year - 2007

Publication title -

diabetes

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.219

H-Index - 330

eISSN - 1939-327X

pISSN - 0012-1797

DOI - 10.2337/db07-0812

Subject(s) - chylomicron , splanchnic , medicine , endocrinology , triglyceride , postprandial , chemistry , lipoprotein lipase , steatosis , adipose tissue , cholesterol , biology , lipoprotein , very low density lipoprotein , insulin , blood flow

Triglyceride-rich lipoproteins, primarily chylomicrons, can contribute to plasma free fatty acid (FFA) concentrations via spillover of fatty acids during intravascular hydrolysis into the venous effluent of some tissues. The present study was undertaken to determine whether spillover occurs in the splanchnic bed of humans.

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