Genome-Wide Scan for Estimated Glomerular Filtration Rate in Multi-Ethnic Diabetic Populations | Zendy

Jeffrey R. Schelling | Zendy; Hanna E. Abboud | Zendy; Susanne B. Nicholas | Zendy; Madeleine V. Pahl | Zendy; John R. Sedor | Zendy; Sharon G. Adler | Zendy; Nedal H. Arar | Zendy; Donald W. Bowden | Zendy; Robert C. Elston | Zendy; Barry I. Freedman | Zendy; Katrina A.B. Goddard | Zendy; Xiuqing Guo | Zendy; Robert L. Hanson | Zendy; Eli Ipp | Zendy; Sudha K. Iyengar | Zendy; Gyungah Jun | Zendy; W.H. Linda Kao | Zendy; Balakuntalam S. Kasinath | Zendy; Paul L. Kimmel | Zendy; Michael J. Klag | Zendy; William C. Knowler | Zendy; Robert G. Nelson | Zendy; Rulan S. Parekh | Zendy; Shan RE Quade | Zendy; Stephen S. Rich | Zendy; Mohammed Saad | Zendy; Marina Scavini | Zendy; Michael W. Smith | Zendy; Kent D. Taylor | Zendy; Cheryl A. Winkler | Zendy; Philip G. Zager | Zendy; Vallabh O. Shah | Zendy

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Genome-Wide Scan for Estimated Glomerular Filtration Rate in Multi-Ethnic Diabetic Populations

Author(s) -

Jeffrey R. Schelling,

Hanna E. Abboud,

Susanne B. Nicholas,

Madeleine V. Pahl,

John R. Sedor,

Sharon G. Adler,

Nedal H. Arar,

Donald W. Bowden,

Robert C. Elston,

Barry I. Freedman,

Katrina A.B. Goddard,

Xiuqing Guo,

Robert L. Hanson,

Eli Ipp,

Sudha K. Iyengar,

Gyungah Jun,

W.H. Linda Kao,

Balakuntalam S. Kasinath,

Paul L. Kimmel,

Michael J. Klag,

William C. Knowler,

Robert G. Nelson,

Rulan S. Parekh,

Shan RE Quade,

Stephen S. Rich,

Mohammed Saad,

Marina Scavini,

Michael W. Smith,

Kent D. Taylor,

Cheryl A. Winkler,

Philip G. Zager,

Vallabh O. Shah

Publication year - 2007

Publication title -

diabetes

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.219

H-Index - 330

eISSN - 1939-327X

pISSN - 0012-1797

DOI - 10.2337/db07-0313

Subject(s) - diabetic nephropathy , linkage (software) , diabetes mellitus , renal function , genetic linkage , proband , quantitative trait locus , ethnic group , nephropathy , medicine , genome scan , microsatellite , genetics , biology , endocrinology , gene , mutation , allele , sociology , anthropology

Diabetic nephropathy, the most common cause of end-stage renal disease, aggregates in families and specific ethnic groups. Deconstructing diabetic nephropathy into intermediate, quantitative phenotypes may increase feasibility of detecting susceptibility loci by genetic screens. Glomerular filtration rate (GFR), which characterizes diabetic nephropathy, was employed as a quantitative trait in a preliminary whole-genome scan.

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