Adipogenesis in Obesity Requires Close Interplay Between Differentiating Adipocytes, Stromal Cells, and Blood Vessels
Author(s) -
Satoshi Nishimura,
Ichiro Manabe,
Masao Nagasaki,
Yumiko Hosoya,
Hiroshi Yamashita,
Hideo Fujita,
Mitsuru Ohsugi,
Kazuyuki Tobe,
Takashi Kadowaki,
Ryozo Nagai,
Seiryo Sugiura
Publication year - 2007
Publication title -
diabetes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.219
H-Index - 330
eISSN - 1939-327X
pISSN - 0012-1797
DOI - 10.2337/db06-1749
Subject(s) - adipogenesis , adipose tissue , angiogenesis , stromal cell , adipocyte , microbiology and biotechnology , cd34 , biology , medicine , 3t3 l1 , stromal vascular fraction , endocrinology , cancer research , stem cell
The expansion of adipose tissue mass seen in obesity involves both hyperplasia and hypertrophy of adipocytes. However, little is known about how adipocytes, adipocyte precursors, blood vessels, and stromal cells interact with one another to achieve adipogenesis.
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