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Importance of Postprandial Glucose in Relation to A1C and Cardiovascular Disease
Author(s) -
Kenneth S. Hershon,
Barbara R. Hirsch,
Ola Odugbesan
Publication year - 2019
Publication title -
clinical diabetes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.931
H-Index - 37
eISSN - 1945-4953
pISSN - 0891-8929
DOI - 10.2337/cd18-0040
Subject(s) - postprandial , medicine , diabetes mellitus , disease , type 2 diabetes , randomized controlled trial , epidemiology , clinical trial , cardiology , intensive care medicine , endocrinology
IN BRIEF This article reviews the evidence regarding the impact of postprandial glucose (PPG) on overall A1C and its relation to cardiovascular disease (CVD). To date, four randomized, controlled trials have evaluated the impact of PPG reduction on CVD; however, only one of these successfully demonstrated a positive effect. Despite this, epidemiological evidence does indicate a cardiovascular benefit of PPG reduction, and agents that can be used to manage PPG in people with type 2 diabetes are also discussed.

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