Higher Venous Bicarbonate Concentration Associated with Hypoxemia, not Acute Mountain Sickness, after Ascent to Moderate Altitude | Zendy

Thomas A. Cumbo | Zendy; Darren Braude | Zendy; Buddha Basnyat | Zendy; Lisa Rabinowitz | Zendy; Andrés G. Lescano | Zendy; Mark Shah | Zendy; Destin J. Radder | Zendy; Govind Bashyal | Zendy; Steven Gambert | Zendy

Open Access

Higher Venous Bicarbonate Concentration Associated with Hypoxemia, not Acute Mountain Sickness, after Ascent to Moderate Altitude

Author(s) -

Thomas A. Cumbo,

Darren Braude,

Buddha Basnyat,

Lisa Rabinowitz,

Andrés G. Lescano,

Mark Shah,

Destin J. Radder,

Govind Bashyal,

Steven Gambert

Publication year - 2006

Publication title -

journal of travel medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.985

H-Index - 59

eISSN - 1708-8305

pISSN - 1195-1982

DOI - 10.2310/7060.2005.12403

Subject(s) - hypoxemia , bicarbonate , medicine , respiratory alkalosis , effects of high altitude on humans , hypoxia (environmental) , alkalosis , venous blood , altitude sickness , oxygen saturation , base excess , anesthesia , oxygen , acidosis , metabolic acidosis , chemistry , organic chemistry , anatomy

The pathophysiology underlying acute mountain sickness (AMS) and excessive hypoxemia at high altitudes is not fully understood. Previous work by our group has demonstrated a significant association between urinary measures of dehydration and bicarbonate retention in subjects developing excessive hypoxemia and AMS at high altitudes. To further characterize these findings, we returned to our original testing site to examine the hypothesis that subjects with lower levels of oxygen saturation and/or AMS would possess higher levels of venous bicarbonate.

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