A Placebo-Controlled Treatment Trial of Blastocystis hominis Infection with Metronidazole | Zendy

Luciano Nigro | Zendy; Licia Larocca | Zendy; Laura Massarelli | Zendy; Ildebrando Patamia | Zendy; Salvatore Minniti | Zendy; Filippo Palermo | Zendy; Bruno Cacopardo | Zendy

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A Placebo-Controlled Treatment Trial of Blastocystis hominis Infection with Metronidazole

Author(s) -

Luciano Nigro,

Licia Larocca,

Laura Massarelli,

Ildebrando Patamia,

Salvatore Minniti,

Filippo Palermo,

Bruno Cacopardo

Publication year - 2006

Publication title -

journal of travel medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.985

H-Index - 59

eISSN - 1708-8305

pISSN - 1195-1982

DOI - 10.2310/7060.2003.31714

Subject(s) - blastocystis , metronidazole , medicine , diarrhea , microbiology and biotechnology , pathogenicity , antibiotics , feces , biology

Blastocystis hominis, previously considered a harmless yeast, is now classified as a protozoan inhabiting the human intestinal tract. The pathogenicity of B. hominis remains controversial and is currently the subject of extensive debate.1- 5 As a result of the uncertainty surrounding the pathogenic role of B. hominis, large-scale treatment trials of B. hominis infection have so far been lacking. In spite of this, several drugs have been reported to be active against the parasite.6-8 The present study was carried out in order to evaluate the efficacy of metronidazole treatment in inducing clinical remission and parasitologic eradication in immunocompetent individuals with B. hominis as the only evident cause of diarrhea.

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