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Crossover Vaccination with Quadrivalent Meningococcal Vaccine (against A/C/Y/W-135) Following Recent Application of Bivalent Meningococcal Vaccine (against A/C): Assessment of Safety and Side Effect Profile
Author(s) -
Annelies WilderSmith,
Nicholas I. Paton
Publication year - 2002
Publication title -
journal of travel medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.985
H-Index - 59
eISSN - 1708-8305
pISSN - 1195-1982
DOI - 10.2310/7060.2002.23943
Subject(s) - medicine , bivalent (engine) , meningococcal vaccine , vaccination , pediatrics , immunology , immunization , antibody , chemistry , organic chemistry , metal
Until May 2000, bivalent A/C meningococcal vaccine was the only available vaccine in Singapore for hajj travelers to Saudi Arabia. Recent worldwide reports of serogroup W-135 meningococcal meningitis associated with hajj returnees necessitated switching to quadrivalent A/C/Y/W-135 vaccine and crossover vaccination of travelers to Saudi Arabia. No safety data are available for quadrivalent vaccine following recent vaccination with bivalent vaccine. We assessed the safety and side effect profile of bivalent, quadrivalent, and quadrivalent meningococcal vaccine after recent vaccination with bivalent vaccine.

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