Serum Antibody Response Induced in Mice after Oral Administration of Three Different Antigens of Enterotoxigenic Escherichia coli in Enteric Coated Microparticles
Author(s) -
Javier A. Adachi,
Zhi-Dong Jiang,
Melinda Cox,
Lindsey Wood,
Herbert L. DuPont,
John J. Mathewson
Publication year - 2006
Publication title -
journal of travel medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.985
H-Index - 59
eISSN - 1708-8305
pISSN - 1195-1982
DOI - 10.2310/7060.2000.00083
Subject(s) - enterotoxigenic escherichia coli , antigen , microbiology and biotechnology , vibrio cholerae , cholera toxin , cholera , antibody , immune system , antibody titer , medicine , toxin , titer , immunology , biology , escherichia coli , enterotoxin , bacteria , biochemistry , genetics , gene
Gastric digestion of these antigens plays an important role, decreasing the ability to deliver antigens to the gut-associated lymphoid tissue. To overcome this obstacle, microencapsulated antigens from enterotoxigenic Escherichia coli (ETEC) were evaluated for oral immunization of mice.
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