Double-Blind, Randomized, Placebo Controlled Pilot Study Evaluating Efficacy and Reactogenicity of an Oral ETEC B-Subunit-Inactivated Whole Cell Vaccine against Travelers’ Diarrhea (Preliminary Report) | Zendy

G Wiedermann | Zendy; Herwig Kollaritsch | Zendy; Michael Kundi | Zendy; AnnMari Svennerholm | Zendy; Ulf Bjare | Zendy

Open Access

Double-Blind, Randomized, Placebo Controlled Pilot Study Evaluating Efficacy and Reactogenicity of an Oral ETEC B-Subunit-Inactivated Whole Cell Vaccine against Travelers’ Diarrhea (Preliminary Report)

Author(s) -

G Wiedermann,

Herwig Kollaritsch,

Michael Kundi,

AnnMari Svennerholm,

Ulf Bjare

Publication year - 2006

Publication title -

journal of travel medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.985

H-Index - 59

eISSN - 1708-8305

pISSN - 1195-1982

DOI - 10.2310/7060.2000.00007

Subject(s) - medicine , enterotoxigenic escherichia coli , diarrhea , reactogenicity , enterotoxin , traveler's diarrhea , immunology , placebo , microbiology and biotechnology , virology , immune system , immunogenicity , biology , escherichia coli , biochemistry , gene , alternative medicine , pathology

Diarrhea caused by enterotoxigenic E.coli (ETEC) is an important health problem in developing countries and in travelers to these areas. In previous trials formulations of ETEC vaccines containing the B-subunit of cholera toxin, which is antigenically similar to the heat labile enterotoxin of ETEC, and the most prevalent colonization factor antigens of ETEC, were shown to stimulate relevant mucosal immune responses in volunteers from Sweden and Egypt.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research