An Expanded Cohort Study of Cancer among Benzene-Exposed Workers in China | Zendy

Song Yin | Zendy; Richard B. Hayes | Zendy; Martha S. Linet | Zendy; Gui-Lan Li | Zendy; Mustafa Dosemeci | Zendy; Lois B. Travis | Zendy; Zhi-Nan Zhang | Zendy; De-Gao Li | Zendy; Wong-Ho Chow | Zendy; Sholom Wacholder | Zendy; William J. Blot | Zendy; The Benzene Study Group | Zendy

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An Expanded Cohort Study of Cancer among Benzene-Exposed Workers in China

Author(s) -

Song Yin,

Richard B. Hayes,

Martha S. Linet,

Gui-Lan Li,

Mustafa Dosemeci,

Lois B. Travis,

Zhi-Nan Zhang,

De-Gao Li,

Wong-Ho Chow,

Sholom Wacholder,

William J. Blot,

The Benzene Study Group

Publication year - 1996

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.2307/3433187

Subject(s) - environmental health , cohort study , cohort , china , medicine , toxicology , biology , geography , archaeology

An expanded cohort study of 74,828 benzene-exposed and 35,805 unexposed workers were followed during 1972 to 1987, based on a previous study in 12 cities in China. A small increase was observed in total cancer mortality among benzene-exposed compared with unexposed workers (relative risk [RR] = 1.2). Statistically significant excesses were noted for leukemia (RR = 2.3), malignant lymphoma (RR = 4.5), and lung cancer (RR = 1.4). When risks were evaluated by leukemia subtype, only acute myelogenous leukemia was significantly elevated (RR = 3.1), although nonsignificant excesses were also noted for chronic myelogenous leukemia (RR = 2.6) and acute lymphocytic leukemia (RR = 2.3). A significant excess was also found for aplastic anemia.

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