Oncological outcome audit of multivisceral resections for primary colorectal cancer: A single centre experience

Colorectal cancer still presents a major health problem, with around 10% of patients, where tumor invades surrounding structures or organs. These patients usually are challenging to treat, even for experienced colorectal surgical team. The decision for performing multivisceral resection is often made intraoperatively, with no sufficient data on the tumor and patient condition. The percentage of perioperative morbidity and mortality is high and oncological outcome is often unfavorable Methods This was retrospective analysis of patients operated on the Department for Colorectal Surgery of the First Surgical Clinic, Clinical Centre of Serbia, Belgrade. En bloc multivisceral resection for the primary adenocarcinoma of the colon and rectum was uniformly performed. Data were collected in prospectively designed database. Follow-up period was minimum 2 years. Patients were analyzed in terms of patohystological, demographical and follow-up data. Survival and time to recurrence were evaluated using Kaplan–Meier method and the log-rank test. Results 213 patients were included in the study The mean age was 59,9 ±12,0 years. Follow-up period was 33,8 ±29 months. Histopathology confirmed true tumor infiltration of the surrounding organ /structure in 126 patients (59,2%). The R0 resection was confirmed in 173 patients (81,2%). 5-year overall survival was 43,4%. 5-year survival for colon patients was 45,9% and in rectal cancer group 40,9%. In N0 group of patients, overall survival in 5year period was 66,7%. N1 and N2 status proved adverse effect on survival (overall 5-year survival 31,3% and 15,9% respectively). 5-year local recurrence rate in R0 group of patients was 17,7% and the percentage of distant metastases in was 66,3% Conclusion