Subclinical hypothyroidism in children and adolescents after hematopoietic stem cells transplantation without irradiation | Zendy

Tatjana Milenković | Zendy; Dragana Vujić | Zendy; Rade Vuković | Zendy; Željko Zečević | Zendy; Ivan Soldatović | Zendy; Katarina Mitrović | Zendy; Sladjana Todorovic | Zendy; Dragan Zdravković | Zendy

Open Access

Subclinical hypothyroidism in children and adolescents after hematopoietic stem cells transplantation without irradiation

Author(s) -

Tatjana Milenković,

Dragana Vujić,

Rade Vuković,

Željko Zečević,

Ivan Soldatović,

Katarina Mitrović,

Sladjana Todorovic,

Dragan Zdravković

Publication year - 2014

Publication title -

vojnosanitetski pregled

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.123

H-Index - 19

eISSN - 2406-0720

pISSN - 0042-8450

DOI - 10.2298/vsp1412123m

Subject(s) - medicine , subclinical infection , total body irradiation , hematopoietic stem cell transplantation , thyroid function , thyroid , transplantation , pediatrics , cohort , chemotherapy , cyclophosphamide

Although total body irradiation (TBI) was considered to be the primary cause of thyroid dysfunction following hematopoietic stem cells transplantation (HSCT), a significant prevalence of subclinical hypothyroidism after HSCT with chemotherapy-only conditioning regimens has been observed in several studies. The aim of this study was to assess changes in thyroid stimulating hormone (TSH) levels in children after HSCT, without the use of irradiation at any time in the course of the treatment.

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