Chromosomal instability in patients with Fanconi anemia from Serbia
Author(s) -
Sanja Cirkovic,
Marija GućŠćekić,
Dragana Vujić,
Dragan Mićić,
Dejan Škorić
Publication year - 2014
Publication title -
vojnosanitetski pregled
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.123
H-Index - 19
eISSN - 2406-0720
pISSN - 0042-8450
DOI - 10.2298/vsp1404368c
Subject(s) - fanconi anemia , chromosome instability , medicine , gastroenterology , anemia , disease , pediatrics , chromosome , genetics , dna repair , biology , dna , gene
Fanconi anemia (FA) is a rare hereditary disease in a heterogeneous group of syndromes, so-called chromosome breakage disorders. Specific hypersensitivity of its cells to chemical agents, such as diepoxybutane (DEB), was used as a part of screening among patients with clinical suspicion of FA. The aim of this study was to determine chromosomal instability in patients with FA symptoms in Serbia.
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