Experimental closure of gunshot wounds by fibrin glue with antibiotics in pigs
Author(s) -
Nebojsa Djenic,
Milan Višnjić,
Saša Dragović,
Vladmila Bojanić,
Zoran Bojanić,
Dragan Djurdjević,
Boris Djindjić,
Miloš Kostov
Publication year - 2015
Publication title -
vojnosanitetski pregled
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.123
H-Index - 19
eISSN - 2406-0720
pISSN - 0042-8450
DOI - 10.2298/vsp131106050d
Subject(s) - fibrin glue , medicine , surgery , fibrous joint , antibiotics , fibrin , absorbable suture , chemistry , immunology , biochemistry
Gunshot wounds caused by the automatic rifle M70AB2 (AK-47) 7.62 mm, after the primary surgical management, were closed with delayed primary suture during the next four to seven days. This period coincides with the fibroblastic phase of wound healing. Fibrin glue is used as a local hemostatic and as a matrix for the local dosed release of antibiotics. Antibiotics addition to fibrin glue resulted in continuous diffusion into the surrounding next 4 to 7 days. The aim of this study was to create the preconditions for gunshot wounds closing without complications by the application of fibrin glue with antibiotics 24 h after primary surgical treatment.
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