Conversion from calcineurin inhibitors to sirolimus of recipients with chronic kidney graft disease grade iii for a period 2003-2011 | Zendy

Ljiljana Ignjatović | Zendy; R Hrvacević | Zendy; Dragan Jovanović | Zendy; Zoran Kovačević | Zendy; Neven Vavić | Zendy; Violeta Rabrenović | Zendy; Aleksandar Tomić | Zendy; Predrag Aleksić | Zendy; Biljana Drašković-Pavlović | Zendy; A Dujić | Zendy; Zeljko Karan | Zendy; Djoko Maksić | Zendy

Open Access

Conversion from calcineurin inhibitors to sirolimus of recipients with chronic kidney graft disease grade iii for a period 2003-2011

Author(s) -

Ljiljana Ignjatović,

R Hrvacević,

Dragan Jovanović,

Zoran Kovačević,

Neven Vavić,

Violeta Rabrenović,

Aleksandar Tomić,

Predrag Aleksić,

Biljana Drašković-Pavlović,

A Dujić,

Zeljko Karan,

Djoko Maksić

Publication year - 2013

Publication title -

vojnosanitetski pregled

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.123

H-Index - 19

eISSN - 2406-0720

pISSN - 0042-8450

DOI - 10.2298/vsp1309848i

Subject(s) - medicine , calcineurin , sirolimus , urology , proteinuria , renal function , kidney disease , nephrotoxicity , creatinine , hemodialysis , transplantation , kidney transplantation , gastroenterology , surgery , kidney

Tremendous breakthrough in solid organ transplantation was made with the introduction of calcineurin inhibitors (CNI). At the same time, they are potentially nephrotoxic drugs with influence on onset and progression of renal graft failure. The aim of this study was to evaluate the outcome of a conversion from CNI-based immunosuppressive protocol to sirolimus (SRL) in recipients with graft in chronic kidney disease (CKD) grade III and proteinuria below 500 mg/day.

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