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Expression of matrix metalloproteinases 2, 7 and 9 in patients with colorectal cancer
Author(s) -
Elena Kostova,
Maja Slaninka-Miceska,
Nikola Labacevski,
Krume Jakovski,
Jasmina Trojachanec,
Emilija Atanasovska,
Vlado Janevski,
Rubens Jovanovik,
Vesna Janevska
Publication year - 2013
Publication title -
vojnosanitetski pregled
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.123
H-Index - 19
eISSN - 2406-0720
pISSN - 0042-8450
DOI - 10.2298/vsp121221024k
Subject(s) - matrix metalloproteinase , immunohistochemistry , medicine , carcinoembryonic antigen , colorectal cancer , metastasis , pathology , extracellular matrix , basement membrane , cancer , stage (stratigraphy) , oncology , biology , paleontology , microbiology and biotechnology
Matrix metalloproteinases (MMPs) are perceived to play a key role in tumor invasion and metastasis by their capacity to degrade basement membranes and extracellular matrix proteins. The aim of this study was to investigate the expressions of MMP-2, MMP-7 and MMP-9 in tumor tissue and their relation to clinicopathologic features in patients with colorectal cancer.

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