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Background/Aim. Retention of fissure sealants and good adaptation to enamel  are essential for their success. Fluoride releasing resin-based materials are  widely accepted for pit and fissure sealing, but newly designed glass  ionomers can serve as a good alternative. The aim of this study was to  evaluate microleakage and sealing ability in vitro, and to clinically assess  two fluoride releasing fissure sealants. Methods. The sample for experimental  study consisted of 20 freshly extracted intact human third molars, divided in  two experimental groups according to the sealing material: fluoride releasing  resin-based (Heliosel F) and glass ionomer (Fuji Triage) material. Digital  images and scanning electron microscope were used to assess microleakage and  adaptation ability. Sample for clinical study consisted of 60 children, aged  6-8 years, with high caries risk, divided in two groups according to the  sealant material. Fissure sealant was applied to all erupted, caries-free  first permanent molars. Sealants were evaluated after 3, 6 and 12 months  using modified Ryge criteria for retention, marginal adaptation, colour  match, surface smoothness and caries. Results. Microleakage was detected in  more than half of the specimen, without significant differences between the  two groups (p > 0.05). Both materials exhibited acceptable sealing ability.  Complete retention at the end of the observation period was 81.8% for  resin-based, and 21.1% for glass-ionomer fissure sealant (p < 0.001). The  presence of caries in sealed molars has been detected in one patient in both  groups. During the 12-month observation period, Helioseal F demonstrated  better retention, marginal adaptation and surface smoothness (p < 0.001).  There were no differences between the two materials regarding caries and  color match (p > 0.05). Conclusion. Both tested materials demonstrate  satisfactory clinical and caries prophylactic characteristics that justify  their use in contemporary preventive dentistry

Microleakage, adaptation ability and clinical efficacy of two fluoride releasing fissure sealants