Evaluation of coagulation factors in fresh frozen plasma treated with riboflavin and ultraviolet light | Zendy

Ana Antić | Zendy; Zoran Stanojković | Zendy; Lana Mačukanović-Golubović | Zendy; Marija Jelić | Zendy

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Evaluation of coagulation factors in fresh frozen plasma treated with riboflavin and ultraviolet light

Author(s) -

Ana Antić,

Zoran Stanojković,

Lana Mačukanović-Golubović,

Marija Jelić

Publication year - 2012

Publication title -

vojnosanitetski pregled

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.123

H-Index - 19

eISSN - 2406-0720

pISSN - 0042-8450

DOI - 10.2298/vsp1201022a

Subject(s) - riboflavin , coagulation , whole blood , fresh frozen plasma , ultraviolet light , medicine , blood plasma , blood collection , coagulation testing , chemistry , platelet , food science , surgery , immunology , photochemistry , emergency medicine

Pathogen inactivation in blood products using riboflavin and ultraviolet (UV) light represents a proactive approach to blood safety, not only for known infectious agents but also for new ones or not yet recognized as threats to the blood supply. This method inactivates a virus, bacteria, fungus, or protozoan pathogen from the blood product without damaging its function or shelf-life. The aim of the study was to study the influence of photoinactivation using riboflavin on the concentration of coagulation factors and coagulation inhibitors in plasma that was treated before freezing.

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