Expression of regulatory proteins and proliferative activity in relation to phenotypic characteristics of upper urothelial carcinoma | Zendy

Zana Dolićanin | Zendy; Ljubinka Janković Veličković | Zendy; Biljana Djordjević | Zendy; Milan Višnjić | Zendy; Ivana Pešić | Zendy; Ana Ristić-Petrović | Zendy; Vesna Marjanović | Zendy

Open Access

Expression of regulatory proteins and proliferative activity in relation to phenotypic characteristics of upper urothelial carcinoma

Author(s) -

Zana Dolićanin,

Ljubinka Janković Veličković,

Biljana Djordjević,

Milan Višnjić,

Ivana Pešić,

Ana Ristić-Petrović,

Vesna Marjanović

Publication year - 2011

Publication title -

vojnosanitetski pregled

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.123

H-Index - 19

eISSN - 2406-0720

pISSN - 0042-8450

DOI - 10.2298/vsp1107567d

Subject(s) - cyclin d1 , phenotype , immunohistochemistry , ki 67 , cell cycle , cell growth , cancer research , biology , cyclin , medicine , pathology , cell , gene , genetics , immunology

Deregulation of the normal cell cycle is common in upper urothelial carcinoma (UUC). The aim of this study was to investigate the expression of regulatory proteins of the cell cycle (p53, p16, cyclin D1, HER-2) and proliferative Ki-67 activity in UUC, and to determine their interaction and influence on the phenotypic characteristics of UUC.

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