The role of insulin-like growth factor in prediction and prevention of preterm delivery | Zendy

Mirjana Bogavac | Zendy; Nataša Simin | Zendy; Milan Ranisavljević | Zendy; Ljiljana Budisic | Zendy

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The role of insulin-like growth factor in prediction and prevention of preterm delivery

Author(s) -

Mirjana Bogavac,

Nataša Simin,

Milan Ranisavljević,

Ljiljana Budisic

Publication year - 2010

Publication title -

vojnosanitetski pregled

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.123

H-Index - 19

eISSN - 2406-0720

pISSN - 0042-8450

DOI - 10.2298/vsp1011883b

Subject(s) - medicine , premature rupture of membranes , obstetrics , gestation , pregnancy , gestational age , prom , preterm delivery , fetus , gynecology , birth weight , obstetrics and gynaecology , genetics , biology

Prediction and prevention of preterm delivery remain great challenge. It is important to include in everyday medical practice determination of certain markers that could help identifying pregnant women with preterm delivery. Insulinlike growth factor (IGF) is involved in the control mechanism of fetal and placental growth and development. The aim of this study was to examine the presence of insulin-like growth factor binding protein 1 (IGFBP-1) in cervicovaginal secretion of pregnant women with symptoms of preterm labor, but with apparently intact fetal membranes and to point out a possible application of the strip test for detection of phlGFBP-1 in diagnosis of preterm premature rupture of total membranes (PPROM) in everyday medical practice.

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