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Use of recombinant factor VIIa in the treatment of massive retroperitoneal bleeding due to severe necrotizing pancreatitis
Author(s) -
Branislav Stefanović,
Branislava Stefanović,
Srdjan Mijatović,
Dejan Radenković,
Nada Popović,
Ana Šijački,
Vesna Lačković
Publication year - 2009
Publication title -
vojnosanitetski pregled
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.123
H-Index - 19
eISSN - 2406-0720
pISSN - 0042-8450
DOI - 10.2298/vsp0911928s
Subject(s) - medicine , surgery , recombinant factor viia , coagulopathy , tamponade , pancreatitis , hemostasis , disseminated intravascular coagulation , sepsis , discontinuation , bleed , anesthesia
Recently, a growing number of case reports and case series have suggested that the use of recombinant activated factor VII (rFVIIa) may be effective in treatment of patients with non-hemophilic acquired coagulopathy not responding to conventional treatment such as major surgery, major trauma, sepsis, necrotizing pancreatitis and bleeding due to cerebral arteriovenous malformations.

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