Hydrolysis of cefazolin by enzymes produced by Pseudomonas aeruginosa after exposure to ceftazidime in vitro | Zendy

Paraskevi Papaioannidou | Zendy; Vassilios Nitsas | Zendy; Vassiliki MirtsouFidani | Zendy

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Hydrolysis of cefazolin by enzymes produced by Pseudomonas aeruginosa after exposure to ceftazidime in vitro

Author(s) -

Paraskevi Papaioannidou,

Vassilios Nitsas,

Vassiliki MirtsouFidani

Publication year - 2009

Publication title -

vojnosanitetski pregled

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.123

H-Index - 19

eISSN - 2406-0720

pISSN - 0042-8450

DOI - 10.2298/vsp0910785p

Subject(s) - ceftazidime , cefazolin , pseudomonas aeruginosa , cephalosporin , microbiology and biotechnology , antibiotics , chemistry , minimum inhibitory concentration , bacteria , biology , genetics

Sometimes resistance of Pseudomonas aeruginosa (Ps. aeruginosa) is developed during antibiotic treatment, in spite of the initial susceptibility in vitro. The aim of this study was to use an in vitro model for the study of the development of resistant strains of Ps. aeruginosa after a short exposure to ceftazidime, and to study the hydrolysing capacity of beta-lactamases produced by the resistant strains.

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