Ursodeoxycholic acid for treatment of cholestasis in patients with hepatic amyloidosis | Zendy

D Faust | Zendy; Bora Akoglu | Zendy; Gordana Ristić | Zendy; Vladan Milović | Zendy

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Ursodeoxycholic acid for treatment of cholestasis in patients with hepatic amyloidosis

Author(s) -

D Faust,

Bora Akoglu,

Gordana Ristić,

Vladan Milović

Publication year - 2009

Publication title -

vojnosanitetski pregled

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.123

H-Index - 19

eISSN - 2406-0720

pISSN - 0042-8450

DOI - 10.2298/vsp0906482f

Subject(s) - ursodeoxycholic acid , cholestasis , medicine , amyloidosis , gastroenterology , bile acid

Amyloidosis represents a group of different diseases characterized by extracellular accumulation of pathologic fibrillar proteins in various tissues and organs. Severe amyloid deposition in the liver parenchyma has extrahepatic involvement predominantly in the kidney or heart. We evaluated the effect of ursodeoxycholic acid, in four patients with severe hepatic amyloidosis of different etiologies, who presented with increased alkaline phosphatase and gamma-glutamyl transferase.

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