Determination of carbamazepine in serum and saliva samples by high performance liquid chromatography with ultraviolet detection | Zendy

Snežana Djordjević | Zendy; Vesna Kilibarda | Zendy; Tomislav Stojanović | Zendy

Open Access

Determination of carbamazepine in serum and saliva samples by high performance liquid chromatography with ultraviolet detection

Author(s) -

Snežana Djordjević,

Vesna Kilibarda,

Tomislav Stojanović

Publication year - 2009

Publication title -

vojnosanitetski pregled

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.123

H-Index - 19

eISSN - 2406-0720

pISSN - 0042-8450

DOI - 10.2298/vsp0905347d

Subject(s) - saliva , carbamazepine , chromatography , chemistry , therapeutic drug monitoring , detection limit , quantitative analysis (chemistry) , high performance liquid chromatography , pharmacokinetics , pharmacology , medicine , epilepsy , biochemistry , psychiatry

Carbamazepine is antiepileptic drug widely used for the treatment of epilepsy. Due to low therapeutic index of carbamazepine there is a need for routine measuring its concentrations in biological fluids. The aim of the study was to describe a method for concomitant determination of carbamazepine in the serum and saliva.

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