Impact of intensive insulin treatment on the development and consequences of oxidative stress in insulin-dependent diabetes mellitus | Zendy

Radivoj Kocić | Zendy; Dušica Pavlović | Zendy; Gordana Kocić | Zendy

Open Access

Impact of intensive insulin treatment on the development and consequences of oxidative stress in insulin-dependent diabetes mellitus

Author(s) -

Radivoj Kocić,

Dušica Pavlović,

Gordana Kocić

Publication year - 2007

Publication title -

vojnosanitetski pregled

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.123

H-Index - 19

eISSN - 2406-0720

pISSN - 0042-8450

DOI - 10.2298/vsp0709623k

Subject(s) - insulin , medicine , diabetes mellitus , malondialdehyde , xanthine oxidase , oxidative stress , endocrinology , catalase , lipid peroxidation , chemistry , biochemistry , enzyme

The aim of this study, which included patients with insulin-dependent diabetes mellitus, was to determine the influence of the application of various treatment modalities (intensive or conventional) on the total plasma antioxidative capacity and lipid peroxidation intensity expressed as malondialdehyde (MDA) level, catalase and xanthine oxidase activity, erythrocyte glutatione reduced concentration (GSH RBC), erythrocyte MDA level (MDA RBC), as well as susceptibility of erythrocyte to H2O2-induced oxidative stress.

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