Mycophenolate mofetil combined with steroids: New experiences in the treatment of idiopathic retroperitoneal fibrosis
Author(s) -
Katarina Obrenčević,
Dragan Jovanović,
Zoran Kovačević,
R Hrvacević,
Ljiljana Ignjatović,
Mirjana Mijušković
Publication year - 2007
Publication title -
vojnosanitetski pregled
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.123
H-Index - 19
eISSN - 2406-0720
pISSN - 0042-8450
DOI - 10.2298/vsp0706385o
Subject(s) - medicine , retroperitoneal fibrosis , prednisone , ureterolysis , azathioprine , urology , surgery , hydronephrosis , gastroenterology , fibrosis , disease , urinary system
[corrected] Idiopathic retroperitoneal fibrosis (IRF) is an uncommon disease characterized by a retroperitoneal fibrotic tissue that often involve the ureters, leading to the obstructive nephropathy and variable impairment of renal function. Findings strongly suggest an autoimmune etiology. Surgery, medical treatment with immunosuppressive drugs, or a combination of both are proposed. The optimal treatment has not been established yet. The aim of this study was to present our experience with combined immunosuppressive therapy of IRF, steroids (S) and mycophenolate mofetil (MMF).
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