Polymorphisms in the genes of citohrom oxidase P450 2D6 (CYP2D6), paraoxonase 1 (PON1) and apolipoproteine E (APOE) as risk factors for Parkinson's disease | Zendy

Gordana Djuric | Zendy; Marina Svetel | Zendy; Nikolaevic Illarioskin | Zendy; Natasa Dragadjevic | Zendy; Jelena Gavrilović | Zendy; Vladimir Kostić | Zendy

Open Access

Polymorphisms in the genes of citohrom oxidase P450 2D6 (CYP2D6), paraoxonase 1 (PON1) and apolipoproteine E (APOE) as risk factors for Parkinson's disease

Author(s) -

Gordana Djuric,

Marina Svetel,

Nikolaevic Illarioskin,

Natasa Dragadjevic,

Jelena Gavrilović,

Vladimir Kostić

Publication year - 2007

Publication title -

vojnosanitetski pregled

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.123

H-Index - 19

eISSN - 2406-0720

pISSN - 0042-8450

DOI - 10.2298/vsp0701025d

Subject(s) - pon1 , paraoxonase , apolipoprotein e , cyp2d6 , disease , medicine , genetics , gene , genotype , biology , oxidative stress

The presence of Parkinson's disease (PD) among the members of a family is a clear indication of the significance of genetics in its development. In spite of that, the majority of patients with PD shows a sporadic form of the disease induced as a result of interaction of both environmental and genetic factors. The aim of this study was to examine the effects of polymorphisms in the genes of cytohrome P450 2D6(CYP2D6), paraoxonase 1 (PON 1) and apolipoprotein E (APOE), as risk factors for PD.

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