Preparation and testing of buffered eye drops containing pilocarpine chloride with timolol maleate | Zendy

Danijela Rakic | Zendy; Mirjana Antunović | Zendy

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Preparation and testing of buffered eye drops containing pilocarpine chloride with timolol maleate

Author(s) -

Danijela Rakic,

Mirjana Antunović

Publication year - 2006

Publication title -

vojnosanitetski pregled

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.123

H-Index - 19

eISSN - 2406-0720

pISSN - 0042-8450

DOI - 10.2298/vsp0610873r

Subject(s) - timolol , pilocarpine , chemistry , chromatography , chloride , glaucoma , high performance liquid chromatography , medicine , ophthalmology , organic chemistry , psychiatry , epilepsy

In glaucoma therapy beta-blocator, timolol-maleate, is the first-line medicine of selection, whereas a miotic, pilocarpine chloride, is one of the oldest medicines used for the treatment of this illness. They are applied as eye drops. In order to achieve a better therapeutic effect and improve life quality of the ill, we produced and tested eye drops formulations based on combining pilocarpinechloride and timolol maleate in buffers of diferent pH values.

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