Evaluation of the degree of clinical rheumatoid arthritis activity based on the concentrations of cytokines TNF-alpha, IL-12, IL-15, and IL-18 in serum and synovial fluid | Zendy

Ljiljana Petrović-Rackov | Zendy

Open Access

Evaluation of the degree of clinical rheumatoid arthritis activity based on the concentrations of cytokines TNF-alpha, IL-12, IL-15, and IL-18 in serum and synovial fluid

Author(s) -

Ljiljana Petrović-Rackov

Publication year - 2006

Publication title -

vojnosanitetski pregled

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.123

H-Index - 19

eISSN - 2406-0720

pISSN - 0042-8450

DOI - 10.2298/vsp0601021p

Subject(s) - rheumatoid arthritis , medicine , synovial fluid , pathogenesis , arthritis , gastroenterology , proinflammatory cytokine , tumor necrosis factor alpha , cytokine , immunology , clinical significance , inflammation , pathology , osteoarthritis , alternative medicine

Experimental in vitro and in vivo investigations in a mouse model have proved that TNF-alpha, IL12, IL-15 and IL18 participate in the pathogenesis of erosive inflammatory arthritis. The aim of this research was to determine the clinical significance of cytokines in the evaluation of the activity of rheumatoid arthritis (RA).

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