Expression of p53 protein in Barrett’s adenocarcinoma and adenocarcinoma of the gastric cardia and antrum | Zendy

Ivan Jovanović | Zendy; Vera Todorovic | Zendy; Tomica Milosavljević | Zendy; Marijan Micev | Zendy; Predrag Peško | Zendy; Miloš Bjelović | Zendy; Yoannis Mouzas | Zendy; Maria Tzardi | Zendy

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Expression of p53 protein in Barrett’s adenocarcinoma and adenocarcinoma of the gastric cardia and antrum

Author(s) -

Ivan Jovanović,

Vera Todorovic,

Tomica Milosavljević,

Marijan Micev,

Predrag Peško,

Miloš Bjelović,

Yoannis Mouzas,

Maria Tzardi

Publication year - 2005

Publication title -

vojnosanitetski pregled

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.123

H-Index - 19

eISSN - 2406-0720

pISSN - 0042-8450

DOI - 10.2298/vsp0512879j

Subject(s) - adenocarcinoma , immunostaining , antrum , pathology , esophagus , medicine , gastroenterology , esophagogastric junction , immunohistochemistry , stomach , cancer

Most studies of esophageal and gastric adenocarcinomas have shown a very high rate of p53 gene mutation and/or protein overexpression, but the influence of the tumour site upon the frequency of p53 protein expression has not been evaluated (gastroesophageal junction, Barret's esophagus, and antrum). The aim of our study was to analyze the correlation between the selected clinico-pathological parameters, and p53 protein overexpression in regards to the particular tumour location.

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