Extreme hypertriglyceridemia in an infant with hemophagocytic lymphohistiocytosis and hydroxycobalamin deficiency | Zendy

Lidija Dokmanović | Zendy; Nada Krstovski | Zendy; Jelena Lazić | Zendy; Predrag Rodić | Zendy; Goran Milošević | Zendy; Srdja Janković | Zendy; Dragana Janić | Zendy

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Extreme hypertriglyceridemia in an infant with hemophagocytic lymphohistiocytosis and hydroxycobalamin deficiency

Author(s) -

Lidija Dokmanović,

Nada Krstovski,

Jelena Lazić,

Predrag Rodić,

Goran Milošević,

Srdja Janković,

Dragana Janić

Publication year - 2015

Publication title -

srpski arhiv za celokupno lekarstvo

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.135

H-Index - 17

eISSN - 2406-0895

pISSN - 0370-8179

DOI - 10.2298/sarh1512744d

Subject(s) - hemophagocytosis , hepatosplenomegaly , hemophagocytic lymphohistiocytosis , medicine , hypertriglyceridemia , hypofibrinogenemia , immunology , pediatrics , pancytopenia , bone marrow , disease , triglyceride , cholesterol , fibrinogen

Hemophagocytic lymphohistiocytosis (HLH) is a severe hyperinflammatory condition characterized by fever, cytopenias, hepatosplenomegaly and hemophagocytosis. HLH may be primary or secondary to infection, autoimmune disease or malignancy. Hypertriglyceridemia is a common abnormality in HLH and one of the HLH-2004 diagnostic criteria.

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