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Prostaglandin E2 in apical tissue fluid and postoperative pain in intact and teeth with large restorations in two endodontic treatment visits
Author(s) -
Djurica Grga,
Bojan Dželetović,
Marija Damjanov,
Ljiljana Hajduković
Publication year - 2013
Publication title -
srpski arhiv za celokupno lekarstvo
Language(s) - English
Resource type - Journals
eISSN - 2406-0895
pISSN - 0370-8179
DOI - 10.2298/sarh1302017g
Subject(s) - medicine , dentistry , prostaglandin e2 , pulp (tooth) , asymptomatic , prostaglandin , visual analogue scale , edema , anesthesia
Acute periapical inflammation is the most common cause of postoperative pain developing as a result of mechanical, chemical and/or microbial injury of periapical tissue. The major inflammatory event responsible for periapical pain is increased vasodilatation and vascular permeability, partly caused by prostaglandin E2, with consequent edema, which leads to the compression of nerve fibers.

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