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Hormones of thyroid gland in sera of rats treated with different dose of concentrated potassium iodine solutions
Author(s) -
L. Marković,
Violeta Mihailović-Vučinić,
Jelena Aritonović
Publication year - 2010
Publication title -
srpski arhiv za celokupno lekarstvo
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 17
eISSN - 2406-0895
pISSN - 0370-8179
DOI - 10.2298/sarh1006323m
Subject(s) - medicine , thyroid , iodine , thyroiditis , autoimmune thyroiditis , endocrinology , hormone , necrosis , materials science , metallurgy
Potassium iodine (KI) is used as a drug therapy for treating numerous diseases such as small-vessel vasculitis, erythema nodosum, vasculitis nodularis, Sweet's syndrome, tuberculosis and granulomatosis, and for iodized salt. At the same time, KI can be harmful. Iodine intake may increase the frequency of thyroiditis in humans, and may induce the occurrence of experimental thyroiditis (ET) in animals. Investigations on an experimental model for the examination of thyroiditis in Wistar rats have clearly showed morphological changes in the rat thyroid evoked by KI administration.

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