Determination of linuron in chamomile by LC-MS/MS using the QuEChERS extraction method

Linuron is a selective herbicide used for the control of broadleaf weeds. Its mode of action is\udthe inhibition of photosynthesis. The QuEChERS method for extraction of linuron residues from\udchamomile was used. The LC–MS/MS method was used for determination of linuron residues. Its\udlinearity was studied in a range of 0.025-0.50 μg/ml using matrix-matched calibration, and the\uddetermination coefficient (R2) was higher than 0.99. Blank chamomile samples were spiked with\udlinuron solution at three concentration levels yielding recoveries of over 90%. The internal standard\udadded in all samples was isoproturon–d6. There were no linuron residues in chamomile flowers,\udwhile the residues ranged from 0.010 to 0.040 mg/kg in the flower stalk samples