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The soil-borne pathogen Cladobotryum dendroides causes cobweb disease of button\udmushroom (Agaricus bisporus) and its significant yield losses. Casing soil disinfection by toxic\udformaldehyde is a widespread practice. The aim of this study was to investigate the potential of\udtwo environmentally friendly substances, colloidal silver and peracetic acid, against C. dendroides.\udTheir biological efficacy (impact on mushroom yield), effectiveness (disease control) and type\udof interactions between them and the fungicide prochloraz-manganese were evaluated.\udBlack peat/lime casing soil was applied to a colonized substrate with the white button\udmushroom strain 737, then inoculated with C. dendroides and treated with the fungicide\udprochloraz-manganse and two environmentally friendly disinfectants based on peracetic\udacid and colloidal silver. The effects of fungicides on mushroom productivity were evaluated\udas biological efficacy and calculated as a ratio of fresh weight of total mushroom yield to\udthe weight of dry substrate. Fungicide effectiveness and synergy factor were calculated by\udAbbott’s (1925) formula. Tests for synergism between prochloraz-manganese and both other\udsubstances were performed using Limpel’s formula.\udThe highest biolgical efficacy, exceeding 92.00, was achieved in treatments with prochlorazmanganese,\udapplied alone or in combination with both other disinfectants. The highest\udeffectiveness of 93.33% was attained in treatments with peracetic acid combined with\udprochloraz-manganese. Trials against cobweb disease revealed a synergistic reaction between\udthe fungicide and peracetic acid and antagonistic between the fungicide and colloidal silver.\udPeracetic acid provided better disease control, compared to colloidal silver applied alone or in\udcombination with the fungicide. Based on these findings, peracetic acid should be recomended\udas an environmentally friendly casing soil disinfectant against cobweb disease of A. bisporus

Possibility of environmentally-safe casing soil disinfection for control of cobweb disease of button mushroom