English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Amiodarone treatment is associated with the occurrence of thyroid  dysfunction. The aim was to determine the incidence of amiodarone-induced  thyroid dysfunctions and the influence of gender, age, treatment duration,  goiter, thyroid antibodies, thyroid echogenicity and family history on their  appearance. Of 248 consecutive patients, 144 males and 104 females, referred  to thyroid status screening, 16% were with clinical dysfunction, 21% with  sub-clinical dysfunction and 63% were euthyroid. The presence of goiter and  thyroid peroxidase antibodies were the significant individual predictive  factors for the occurrence of clinical dysfunction, and in the multivariate  regression model, the presence of goiter was a significant predictive factor  with the prognostic value of 80%. For sub-clinical dysfunction, the  significant individual predictive factors were female gender and the presence  of goiter, as well as in the multivariate regression model, with the  prognostic value of 74.5% for female gender and 77.5 % for the presence of  goiter. It is necessary to check the thyroid status both before and during  amiodarone treatment. Administration of other anti-arrhythmic drugs and/or  more frequent check-ups of the thyroid status should be taken into  consideration in patients at higher risk, i.e. women with positive thyroid  peroxidase antibodies and goiter

Incidence of amiodarone-induced thyroid dysfunction and predictive factors for their occurrence